Derek Hargrove

Graduate Student

School of Pharmacy


Education

2006-2011      B.S.E. Chemical Engineering      University of Connecticut

2006-2011      B.A. German Studies      University of Connecticut

2013-Present      PhD. Student in Pharmaceutical Sciences      University of Connecticut

 

Research Appointments

2010-2011      Undergraduate Researcher in Chemical Engineering       University of Connecticut

 

Professional Appointments

2011-2013       Lab Technician      Henkel Corporation, Rocky Hill, CT

 

Professional Societies

2013-Present      Member American Association of Pharmaceutical Sciences (AAPS)

2016-Present      Member, International Society of Pharmaceutical Engineering

 

Honors and Awards

2013-Present      Multicultural Scholars Fellowship  School of Pharmacy, University of Connecticut

2016-Present      R.E. Singiser Memorial Fellowship  School of Pharmacy, University of Connecticut

11/2015      Best Oral Presentation Award  SAPA-CT Joint Scientific Symposium

10/2014      Best Poster Award  Nanomedicine Drug Delivery Symposium

 

Oral Presentations

11/2016          SAPA-CT Joint Scientific Symposium

Hargrove D, Liang B, Gonzalez-Fajardo L, Tran TH, Salner A, and Lu X. Tumor-Nanoparticle Interaction of  Intraperitoneally Delivered Neutron Activatable Nanoparticles In Vivo and In a 3D Tumor Spheroid Model

10/2014          Nanomedicine Drug Delivery Symposium

Hargrove D, Liang B, Gonzalez-Fajardo L, Tran TH, Salner A and Lu X. Tumor-nanoparticle interaction of intraperitoneally delivered neutron activatable nanoparticles in vivo and in a 3D tumor spheroid model

 

Poster Presentation

Hargrove D, Liang B, Gonzalez-Fajardo L, Salner A, and Lu X, Understanding Tumor-Nanoparticle Interaction of Intraperitoneally Delivered Neutron Activatable Mesoporous Silica Nanoparticles For the Treatment of Peritoneal Metastasis. 2016, International Nanomedicine Drug Delivery Symposium, Baltimore, Maryland, Novemeber 16-18

 

Publications

Hargrove D, Lu X. Neutron Activatable Nanoparticles for Intraperitoneal Radiation Therapy. Cancer Nanotechnology, Methods in Molecular Biology, Vol. 1530, chapter 24. Springer. ISBN: 978-1-4939-6644-8

 Fu Q, Hargrove D, Lu X.  Improving Paclitaxel Pharmacokinetics by Using Tumor-Specific Mesoporous Silica nanoparticles with Intraperitoneal Delivery. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016, 12: 1951–1959. (NIHMS827684)

Chen J, Ma X, Dong Q, Song D, Hargrove D, Vora S, Ma A, Lu X, and yu L, Self-Healing of Thermally-Induced, Biocompatible and Biodegradable Protein Hydrogel, RSC Advances 2016 6, 56183-56192 DOI: 10.1039/C6RA11239K

Ma X, Wang T, Song D, Hargrove D, Dong Q, Luo Z, Chen J, Lu X, Luo Y, Fan T, and  Lei Y,  Protein Microspheres with Unique Green and Red Autofluorescence for Noninvasively Tracking and Modeling Their in Vivo Biodegradation ACS Biomaterials Science & Engineering 2016 2 (6), 954-962 DOI: 10.1021/acsbiomaterials.6b00048

Gonzalez-Fajardo L, Mahajan L, Ndaya D, Hargrove D, Manautou J, Liang B, Chen M, Kasi R, Lu X, Reduced in vivo toxicity of doxorubicin by encapsulation in cholesterol-containing self-assembled nanoparticles, Pharmacological Research, Volume 107, May 2016, Pages 93-101, ISSN 1043-6618, http://dx.doi.org/10.1016/j.phrs.2016.03.006.

Ma X, Sun X, Hargrove D, et al. A Biocompatible and Biodegradable Protein Hydrogel with Green and Red Autofluorescence: Preparation, Characterization and In Vivo Biodegradation Tracking and Modeling. Scientific Reports. 2016;6:19370. doi:10.1038/srep19370.

Tran TH, Nguyen CT, Gonzalez-Fajardo L, Hargrove D, Song D, Deshmukh P, Mahajan L, Ndaya D, Lai L, Kasi RM, and Lu X. Long circulating self-assembled nanoparticles from cholesterol-containing brush-like block copolymers for improved drug delivery to tumors. Biomacromolecules. 2014, Oct. 15 DOI: 10.1021/bm5013822

Contact Information
Emailderek.hargrove@uconn.edu