Derek Hargrove
Ph.D. Graduate/Post-Doctoral Fellow
Alexion Pharmaceuticals
Education
2020-Present Post-Doctoral Research Fellow, University of Connecticut
2013-2020 Ph.D. Candidate in Pharmaceutical Sciences, University of Connecticut
2006-2011 B.S.E. Chemical Engineering, University of Connecticut
2006-2011 B.A. German Studies, University of Connecticut
Research Appointments
2010-2011 Undergraduate Researcher in Chemical Engineering, University of Connecticut
Professional Appointments
2011-2013 Lab Technician, Henkel Corporation, Rocky Hill, CT
Professional Societies
2013-Present Member American Association of Pharmaceutical Sciences (AAPS)
2016-Present Member, International Society of Pharmaceutical Engineering
Honors and Awards
2013-Present Multicultural Scholars Fellowship School of Pharmacy, University of Connecticut
2016-Present R.E. Singiser Memorial Fellowship School of Pharmacy, University of Connecticut
11/2015 Best Oral Presentation Award SAPA-CT Joint Scientific Symposium
10/2014 Best Poster Award Nanomedicine Drug Delivery Symposium
Oral Presentations
11/2016 SAPA-CT Joint Scientific Symposium
Hargrove D, Liang B, Gonzalez-Fajardo L, Tran TH, Salner A, and Lu X. Tumor-Nanoparticle Interaction of Intraperitoneally Delivered Neutron Activatable Nanoparticles In Vivo and In a 3D Tumor Spheroid Model
10/2014 Nanomedicine Drug Delivery Symposium
Hargrove D, Liang B, Gonzalez-Fajardo L, Tran TH, Salner A and Lu X. Tumor-nanoparticle interaction of intraperitoneally delivered neutron activatable nanoparticles in vivo and in a 3D tumor spheroid model
Poster Presentation
Hargrove D, Liang B, Gonzalez-Fajardo L, Salner A, and Lu X, Understanding Tumor-Nanoparticle Interaction of Intraperitoneally Delivered Neutron Activatable Mesoporous Silica Nanoparticles For the Treatment of Peritoneal Metastasis. 2016, International Nanomedicine Drug Delivery Symposium, Baltimore, Maryland, Novemeber 16-18
Publications
Hargrove D, Lu X. Neutron Activatable Nanoparticles for Intraperitoneal Radiation Therapy. Cancer Nanotechnology, Methods in Molecular Biology, Vol. 1530, chapter 24. Springer. ISBN: 978-1-4939-6644-8
Fu Q, Hargrove D, Lu X. Improving Paclitaxel Pharmacokinetics by Using Tumor-Specific Mesoporous Silica nanoparticles with Intraperitoneal Delivery. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016, 12: 1951–1959. (NIHMS827684)
Chen J, Ma X, Dong Q, Song D, Hargrove D, Vora S, Ma A, Lu X, and yu L, Self-Healing of Thermally-Induced, Biocompatible and Biodegradable Protein Hydrogel, RSC Advances 2016 6, 56183-56192 DOI: 10.1039/C6RA11239K
Ma X, Wang T, Song D, Hargrove D, Dong Q, Luo Z, Chen J, Lu X, Luo Y, Fan T, and Lei Y, Protein Microspheres with Unique Green and Red Autofluorescence for Noninvasively Tracking and Modeling Their in Vivo Biodegradation ACS Biomaterials Science & Engineering 2016 2 (6), 954-962 DOI: 10.1021/acsbiomaterials.6b00048
Gonzalez-Fajardo L, Mahajan L, Ndaya D, Hargrove D, Manautou J, Liang B, Chen M, Kasi R, Lu X, Reduced in vivo toxicity of doxorubicin by encapsulation in cholesterol-containing self-assembled nanoparticles, Pharmacological Research, Volume 107, May 2016, Pages 93-101, ISSN 1043-6618, http://dx.doi.org/10.1016/j.phrs.2016.03.006.
Ma X, Sun X, Hargrove D, et al. A Biocompatible and Biodegradable Protein Hydrogel with Green and Red Autofluorescence: Preparation, Characterization and In Vivo Biodegradation Tracking and Modeling. Scientific Reports. 2016;6:19370. doi:10.1038/srep19370.
Tran TH, Nguyen CT, Gonzalez-Fajardo L, Hargrove D, Song D, Deshmukh P, Mahajan L, Ndaya D, Lai L, Kasi RM, and Lu X. Long circulating self-assembled nanoparticles from cholesterol-containing brush-like block copolymers for improved drug delivery to tumors. Biomacromolecules. 2014, Oct. 15 DOI: 10.1021/bm5013822
