Derek Hargrove

Ph.D. Graduate/Post-Doctoral Fellow

Alexion Pharmaceuticals


2020-Present      Post-Doctoral Research Fellow, University of Connecticut

2013-2020           Ph.D. Candidate in Pharmaceutical Sciences, University of Connecticut

2006-2011            B.S.E. Chemical Engineering, University of Connecticut

2006-2011            B.A. German Studies, University of Connecticut

Research Appointments 

2010-2011            Undergraduate Researcher in Chemical Engineering, University of Connecticut

Professional Appointments

2011-2013            Lab Technician, Henkel Corporation, Rocky Hill, CT

Professional Societies

2013-Present      Member American Association of Pharmaceutical Sciences (AAPS)

2016-Present      Member, International Society of Pharmaceutical Engineering

Honors and Awards

2013-Present       Multicultural Scholars Fellowship  School of Pharmacy, University of Connecticut

2016-Present       R.E. Singiser Memorial Fellowship  School of Pharmacy, University of Connecticut

11/2015                Best Oral Presentation Award  SAPA-CT Joint Scientific Symposium

10/2014                Best Poster Award  Nanomedicine Drug Delivery Symposium

Oral Presentations

11/2016               SAPA-CT Joint Scientific Symposium

Hargrove D, Liang B, Gonzalez-Fajardo L, Tran TH, Salner A, and Lu X. Tumor-Nanoparticle Interaction of  Intraperitoneally Delivered Neutron Activatable Nanoparticles In Vivo and In a 3D Tumor Spheroid Model

10/2014              Nanomedicine Drug Delivery Symposium

Hargrove D, Liang B, Gonzalez-Fajardo L, Tran TH, Salner A and Lu X. Tumor-nanoparticle interaction of intraperitoneally delivered neutron activatable nanoparticles in vivo and in a 3D tumor spheroid model

Poster Presentation

Hargrove D, Liang B, Gonzalez-Fajardo L, Salner A, and Lu X, Understanding Tumor-Nanoparticle Interaction of Intraperitoneally Delivered Neutron Activatable Mesoporous Silica Nanoparticles For the Treatment of Peritoneal Metastasis. 2016, International Nanomedicine Drug Delivery Symposium, Baltimore, Maryland, Novemeber 16-18


Hargrove D, Lu X. Neutron Activatable Nanoparticles for Intraperitoneal Radiation Therapy. Cancer Nanotechnology, Methods in Molecular Biology, Vol. 1530, chapter 24. Springer. ISBN: 978-1-4939-6644-8

 Fu Q, Hargrove D, Lu X.  Improving Paclitaxel Pharmacokinetics by Using Tumor-Specific Mesoporous Silica nanoparticles with Intraperitoneal Delivery. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016, 12: 1951–1959. (NIHMS827684)

Chen J, Ma X, Dong Q, Song D, Hargrove D, Vora S, Ma A, Lu X, and yu L, Self-Healing of Thermally-Induced, Biocompatible and Biodegradable Protein Hydrogel, RSC Advances 2016 6, 56183-56192 DOI: 10.1039/C6RA11239K

Ma X, Wang T, Song D, Hargrove D, Dong Q, Luo Z, Chen J, Lu X, Luo Y, Fan T, and  Lei Y,  Protein Microspheres with Unique Green and Red Autofluorescence for Noninvasively Tracking and Modeling Their in Vivo Biodegradation ACS Biomaterials Science & Engineering 2016 2 (6), 954-962 DOI: 10.1021/acsbiomaterials.6b00048

Gonzalez-Fajardo L, Mahajan L, Ndaya D, Hargrove D, Manautou J, Liang B, Chen M, Kasi R, Lu X, Reduced in vivo toxicity of doxorubicin by encapsulation in cholesterol-containing self-assembled nanoparticles, Pharmacological Research, Volume 107, May 2016, Pages 93-101, ISSN 1043-6618,

Ma X, Sun X, Hargrove D, et al. A Biocompatible and Biodegradable Protein Hydrogel with Green and Red Autofluorescence: Preparation, Characterization and In Vivo Biodegradation Tracking and Modeling. Scientific Reports. 2016;6:19370. doi:10.1038/srep19370.

Tran TH, Nguyen CT, Gonzalez-Fajardo L, Hargrove D, Song D, Deshmukh P, Mahajan L, Ndaya D, Lai L, Kasi RM, and Lu X. Long circulating self-assembled nanoparticles from cholesterol-containing brush-like block copolymers for improved drug delivery to tumors. Biomacromolecules. 2014, Oct. 15 DOI: 10.1021/bm5013822

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